Goals of asthma management - A step-care approach

被引:19
作者
Bone, RC
机构
[1] Medical College of Ohio, Toledo, OH
[2] Department of Medicine, Medical College of Ohio, Toledo, OH 43614
关键词
airway hyperresponsiveness; bronchodilator; circadian rhythm; cytokines; inflammatory response; mediators;
D O I
10.1378/chest.109.4.1056
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
The past 15 years have seen a rise in mortality and morbidity resulting from asthma, despite a concurrent rise in general knowledge about the disease. The step-care strategy recognized these changes in its approach to asthma management; however, this approach should be used only with attempts to control environmental allergens. Step-care therapy requires that patients be categorized by the severity of illness. Step-one therapy is used for mild, infrequent symptoms and involves treatment based primarily on inhaled bronchodilators. Step-two therapy is instituted in all asthmatics except the mildest cases; it involves treatment by inhaled corticosteroids, cromolyn, or nedocromil, Step-three treatment targets cases of severe asthma through the use of oral corticosteroids. In all phases of treatment, however, it should be remembered that patient education is of critical importance. Education improves patient compliance and is critical to the successful treatment of asthma.
引用
收藏
页码:1056 / 1065
页数:10
相关论文
共 60 条
[31]   ASTHMA AND EMOTION - A REVIEW [J].
LEHRER, PM ;
ISENBERG, S ;
HOCHRON, SM .
JOURNAL OF ASTHMA, 1993, 30 (01) :5-21
[32]   EFFECT OF AIR-POLLUTION ON THE PREVALENCE OF ASTHMA AND ALLERGY - LESSONS FROM THE GERMAN REUNIFICATION [J].
MAGNUSSEN, H ;
JORRES, R ;
NOWAK, D .
THORAX, 1993, 48 (09) :879-881
[33]   AIRWAYS INFLAMMATION IN NOCTURNAL ASTHMA [J].
MARTIN, RJ ;
CICUTTO, LC ;
SMITH, HR ;
BALLARD, RD ;
SZEFLER, SJ .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1991, 143 (02) :351-357
[34]   DESIGNING THERAPEUTICALLY EFFECTIVE 5-LIPOXYGENASE INHIBITORS [J].
MCMILLAN, RM ;
WALKER, ERH .
TRENDS IN PHARMACOLOGICAL SCIENCES, 1992, 13 (08) :323-330
[35]   CURRENT ISSUES IN THE USE OF THEOPHYLLINE [J].
MILGROM, H ;
BENDER, B .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1993, 147 (06) :S33-S39
[36]   PARASYMPATHETIC NERVOUS-SYSTEM IN NOCTURNAL ASTHMA [J].
MORRISON, JFJ ;
PEARSON, SB ;
DEAN, HG .
BRITISH MEDICAL JOURNAL, 1988, 296 (6634) :1427-1429
[37]   DOES THE EFFECT OF IMMUNOTHERAPY LAST AFTER TERMINATION OF TREATMENT - FOLLOW-UP-STUDY IN PATIENTS WITH GRASS-POLLEN RHINITIS [J].
MOSBECH, H ;
OSTERBALLE, O .
ALLERGY, 1988, 43 (07) :523-529
[38]  
*NAT HEART LUNG BL, DEP HHS PUBL NIH
[39]   A DOUBLE-BLIND, PLACEBO-CONTROLLED EVALUATION OF SUBLINGUAL IMMUNOTHERAPY WITH STANDARDIZED CAT EXTRACT [J].
NELSON, HS ;
OPPENHEIMER, J ;
VATSIA, GA ;
BUCHMEIER, A .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1993, 92 (02) :229-236
[40]  
Nelson HS, 1995, DRUG THER, V333, P499