Solid phase synthesis of structurally diverse tetra substituted pyrimidines for potential use in combinatorial chemistry

被引：6

作者：

Chauhan, PMS ^{[1
]}

Kumar, A ^{[1
]}

机构：

[1] Cent Drug Res Inst, Div Med Chem, Lucknow 226001, Uttar Pradesh, India

来源：

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING | 2002年 / 5卷 / 01期

关键词：

combinatorial chemistry; substituted pyrimidine;

D O I：

10.2174/1386207023330525

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A new pyrimidine based scaffold has been identified for generation of combinatorial libraries using solid phase technique. The utility of the scaffolds was demonstrated by synthesizing small libraries of 12 substituted pyrimidines (4a-41).

引用

页码：93 / 95

页数：3

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