Interleukin-17A and Interleukin-17F: A Tale of Two Cytokines

被引：47

作者：

Dubin, Patricia J. ^{[2
]}

Kolis, Jay K. ^{[1
]}

机构：

[1] LSU Hlth Sci Ctr, Dept Genet, New Orleans, LA 70112 USA

[2] Childrens Hosp Pittsburgh, Rangos Res Ctr, Pittsburgh, PA 15201 USA

来源：

IMMUNITY | 2009年 / 30卷 / 01期

关键词：

IL-17; RECEPTOR; HOST-DEFENSE; CELLS;

D O I：

10.1016/j.immuni.2008.12.010

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

In this issue of Immunity, Ishigame et al. (2009) show that interleukin-17A (IL-17A) mediates autoimmunity whereas both IL-17A and IL-17F are required for mucosal immunity. IL-17A may be more pathologic by inducing proinflammatory cytokines.

引用

页码：9 / 11

页数：3

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