The RCSB Protein Data Bank: new resources for research and education

被引:356
作者
Rose, Peter W. [1 ]
Bi, Chunxiao [1 ]
Bluhm, Wolfgang F. [1 ]
Christie, Cole H. [1 ]
Dimitropoulos, Dimitris [1 ]
Dutta, Shuchismita [2 ]
Green, Rachel K. [2 ]
Goodsell, David S. [3 ]
Prlic, Andreas [1 ]
Quesada, Martha [2 ]
Quinn, Gregory B. [1 ]
Ramos, Alexander G. [1 ]
Westbrook, John D. [2 ]
Young, Jasmine [2 ]
Zardecki, Christine [2 ]
Berman, Helen M. [2 ]
Bourne, Philip E. [1 ,4 ]
机构
[1] Univ Calif San Diego, San Diego Supercomp Ctr, La Jolla, CA 92093 USA
[2] Rutgers State Univ, Dept Chem & Chem Biol, Piscataway, NJ 08854 USA
[3] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA
[4] Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, La Jolla, CA 92093 USA
基金
美国国家科学基金会;
关键词
STRUCTURE ALIGNMENT; SEQUENCE; CLASSIFICATION; BIOLOGY; SEARCH; BLAST; TOOL;
D O I
10.1093/nar/gks1200
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) develops tools and resources that provide a structural view of biology for research and education. The RCSB PDB web site (http://www.rcsb.org) uses the curated 3D macromolecular data contained in the PDB archive to offer unique methods to access, report and visualize data. Recent activities have focused on improving methods for simple and complex searches of PDB data, creating specialized access to chemical component data and providing domain-based structural alignments. New educational resources are offered at the PDB-101 educational view of the main web site such as Author Profiles that display a researcher's PDB entries in a timeline. To promote different kinds of access to the RCSB PDB, Web Services have been expanded, and an RCSB PDB Mobile application for the iPhone/iPad has been released. These improvements enable new opportunities for analyzing and understanding structure data.
引用
收藏
页码:D475 / D482
页数:8
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