Computer screen photo-excited surface plasmon resonance imaging

被引:20
作者
Filippini, Daniel [1 ]
Winquist, Fredrik [1 ]
Lundstrom, Ingemar [1 ]
机构
[1] Linkoping Univ, IFM, Div Appl Phys, S-58183 Linkoping, Sweden
基金
瑞典研究理事会;
关键词
surface plasmon resonance; optical sensing; computer screen photo-assisted technique; biosensors; sensors;
D O I
10.1016/j.aca.2008.07.022
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Angle and spectra resolved surface plasmon resonance (SPR) images of gold and silver thin films with protein deposits is demonstrated using a regular computer screen as light source and a web camera as detector. The screen provides multiple-angle illumination, p-polarized light and controlled spectral radiances to excite surface plasmons in a Kretchmann configuration. A model of the SPR reflectances incorporating the particularities of the source and detector explain the observed signals and the generation of distinctive SPR landscapes is demonstrated. The sensitivity and resolution of the method, determined in air and solution, are 0.145 nm pixel(-1), 0.523 nm, 5.13 x 10(-3) RIU degree(-1) and 6.014 x 10(-4) RIU, respectively, encouraging results at this proof of concept stage and considering the ubiquity of the instrumentation. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:207 / 214
页数:8
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