An integrated genetic map for linkage analysis

被引：28

作者：

Duffy, DL ^{[1
]}

机构：

[1] Queensland Inst Med Res, Herston, Qld 4029, Australia

来源：

BEHAVIOR GENETICS | 2006年 / 36卷 / 01期

关键词：

genetic linkage; map; loess;

D O I：

10.1007/s10519-005-9015-x

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Here I describe an Internet accessible database containing interpolated genetic map positions for 12917 marker loci. These are estimated via locally weighted linear regression (loess) from the Build 35.1 physical map position and the linkage map of Kong, X., and coworkers (2004) Am. J. Hum. Genet. 75:1143-1148. For the pseudoautosomal region, I have interpolated a male map based on the sperm typing data of Lien, S., and coworkers.

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页码：4 / 6

页数：3

相关论文

共 14 条

[1] HumanMSD and MouseMSD: generating genetic maps for human and murine microsatellite markers [J].

Bahlo, M ;

Xing, L ;

Wilkinson, CR .

BIOINFORMATICS, 2004, 20 (17) :3280-3283

[2] Comprehensive human genetic maps: Individual and sex-specific variation in recombination [J].

Broman, KW ;

Murray, JC ;

Sheffield, VC ;

White, RL ;

Weber, JL .

AMERICAN JOURNAL OF HUMAN GENETICS, 1998, 63 (03) :861-869

[3] A metric map of humans: 23,500 loci in 850 bands [J].

Collins, A ;

Frezal, J ;

Teague, J ;

Morton, NE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (25) :14771-14775

[4] A high-resolution recombination map of the human genome [J].

Kong, A ;

Gudbjartsson, DF ;

Sainz, J ;

Jonsdottir, GM ;

Gudjonsson, SA ;

Richardsson, B ;

Sigurdardottir, S ;

Barnard, J ;

Hallbeck, B ;

Masson, G ;

Shlien, A ;

Palsson, ST ;

Frigge, ML ;

Thorgeirsson, TE ;

Gulcher, JR ;

Stefansson, K .

NATURE GENETICS, 2002, 31 (03) :241-247

[5] A combined linkage-physical map of the human genome [J].

Kong, X ;

Murphy, K ;

Raj, T ;

He, C ;

White, PS ;

Matise, TC .

AMERICAN JOURNAL OF HUMAN GENETICS, 2004, 75 (06) :1143-1148

[6] Evidence for heterogeneity in recombination in the human pseudoautosomal region: High resolution analysis by sperm typing and radiation-hybrid mapping [J].

Lien, S ;

Szyda, J ;

Schechinger, B ;

Rappold, G ;

Arnheim, N .

AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 66 (02) :557-566

[7]

LOADER C, 2004, LOCFIT LOCAL REGRESS

[8] The fine-scale structure of recombination rate variation in the human genome [J].

McVean, GAT ;

Myers, SR ;

Hunt, S ;

Deloukas, P ;

Bentley, DR ;

Donnelly, P .

SCIENCE, 2004, 304 (5670) :581-584

[9] Large-scale integration of human genetic and physical maps [J].

Nievergelt, CM ;

Smith, DW ;

Kohlenberg, JB ;

Schork, NJ .

GENOME RESEARCH, 2004, 14 (06) :1199-1205

[10]

R Development Core Team, 2005, R LANG ENV STAT COMP