Mechanism of V(D)J recombination

被引：88

作者：

Bogue, M

Roth, DB

机构：

[1] Dept. of Microbiology and Immunology, Baylor College of Medicine, Immunology M929, Houston, TX 77030

来源：

CURRENT OPINION IN IMMUNOLOGY | 1996年 / 8卷 / 02期

关键词：

D O I：

10.1016/S0952-7915(96)80055-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

V(D)J recombination can be separated into two basic operations: DNA cleavage and joining of broken ends. Our understanding of both reactions has increased substantially in the past year, Major advances include the development of a cell-free system capable of cleavage and the identification of several proteins involved in both V(D)J recombination and double-strand break repair.

引用

页码：175 / 180

页数：6

共 51 条

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