Detection of an occult hepatocellular carcinoma using ultrasound with liver-specific microbubbles

被引：19

作者：

Harvey, Christopher J. ^{[1
]}

Lim, Adrian K. P. ^{[1
]}

Blomley, Martin J. K. ^{[1
]}

Taylor-Robinson, Simon D. ^{[2
]}

Gedroyc, Wladyslaw M. W. ^{[3
]}

Cosgrove, David O. ^{[1
]}

机构：

[1] Hammersmith Hosp, Dept Imaging Sci, Imperial Coll Sch Med, London W12 0NN, England

[2] Hammersmith Hosp, Imperial Coll Sch Med, Div Med, London W12 0NN, England

[3] St Marys Hosp, Dept Imaging, Imperial Coll Sch Med, London W2 1NY, England

来源：

EUROPEAN RADIOLOGY | 2002年 / 12卷 / Suppl 3期

关键词：

Hepatocellular carcinoma; Cirrhosis; Ultrasonography; Liver-specific microbubbles; Ultrasound contrast agents;

D O I：

10.1007/s00330-002-1593-x

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The radiological surveillance of cirrhosis to detect the development of hepatocellular carcinoma (HCC) is problematic because no highly sensitive and specific imaging investigation is available. Ultrasound is typically the first modality used but is less accurate than other imaging modalities. We report the first case of a patient with cirrhosis in whom US imaging with liver-specific microbubbles detected an HCC prior to its detection by MR. The use of liver-specific microbubble US contrast agents is an exciting development in the detection of HCC in chronic liver disease and may help to rectify some of the shortcomings of US.

引用

页码：S70 / S73

页数：4

共 18 条

[1] Phase-inversion sonography during the liver-specific late phase of contrast enhancement: Improved detection of liver metastases [J].

Albrecht, T ;

Hoffmann, CW ;

Schmitz, SA ;

Schettler, S ;

Overberg, A ;

Germer, CT ;

Wolf, KJ .

AMERICAN JOURNAL OF ROENTGENOLOGY, 2001, 176 (05) :1191-1198

[2]

Albrecht T, RADIOLOGY IN PRESS

[3]

Baron R, 1998, IMAGING ONCOLOGY, V1, P169

[4]

BAUER A, 1997, ADV ECHO IMAGING USI, P685

[5] Characterization of unifocal liver lesions with pulse inversion harmonic imaging after Levovist injection: preliminary results [J].

Bertolotto, M ;

Dalla Palma, L ;

Quaia, E ;

Locatelli, M .

EUROPEAN RADIOLOGY, 2000, 10 (09) :1369-1376

[6] Improved imaging of liver metastases with stimulated acoustic emission in the late phase of enhancement with the US contrast agent SH U 508A: Early experience [J].

Blomley, MJK ;

Albrecht, T ;

Cosgrove, DO ;

Patel, N ;

Jayaram, V ;

Butler-Barnes, J ;

Eckersley, RJ ;

Bauer, A ;

Schlief, R .

RADIOLOGY, 1999, 210 (02) :409-416

[7]

Blomley MJK, 1999, EUR RADIOL, V9, P64

[8]

Cosgrove DO, 2001, ABDOMINAL GEN ULTRAS, V1, P67

[9]

de Jode MG, 1999, J HEPATOL, V31, P347

[10] Tissue-specific US contrast agent for evaluation of hepatic and splenic parenchyma [J].

Forsberg, F ;

Goldberg, BB ;

Liu, JB ;

Merton, DA ;

Rawool, NM ;

Shi, WT .

RADIOLOGY, 1999, 210 (01) :125-132

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