Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005

被引:31
作者
Kochel, Tadeusz [1 ,2 ]
Aguilar, Patricia [1 ,2 ]
Felices, Vidal [1 ,2 ]
Comach, Guillermo [3 ]
Cruz, Cristopher [1 ,2 ]
Alava, Aracely [4 ]
Vargas, Jorge [5 ]
Olson, James [1 ,2 ]
Blair, Patrick [1 ,2 ]
机构
[1] USN, Med Res Ctr Detachment, Unit 3800, APO, AA 34031 USA
[2] Amer Embassy, Lima, Peru
[3] BIOMED UC, Lab Reg Diagnost & Invest Dengue & Otras Enfermed, Maracay 2105, Estado Arague, Venezuela
[4] Inst Nacl Higiene & Med Trop Leopoldo Izquieta Pe, Guayaquil, Ecuador
[5] Ctr Nacl Enfermedades Trop, Santa Cruz, Bolivia
关键词
Dengue-3; virus; evolution; transmission;
D O I
10.1016/j.meegid.2008.06.008
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:682 / 688
页数:7
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