Revival of the autoantibody model in rheumatoid arthritis

被引:27
作者
Hirano, T [1 ]
机构
[1] Osaka Univ, Grad Sch Med, Dept Mol Oncol, RIKEN Res Ctr Allergy & Immunol,Lab Cytokine Sign, Suita, Osaka 5650871, Japan
关键词
D O I
10.1038/ni0402-342
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
New evidence revives the old idea that B cells are the principal effectors in rheumatoid arthritis: autoantibodies against a ubiquitous antigen cause joint-specific disease. The resolution of these conflicting hypotheses resides in the joint itself. "(On-Ko-Chi-Shin)-the new idea resides within the old".
引用
收藏
页码:342 / 344
页数:4
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