The HPA axis in major depression: classical theories and new developments

被引：1362

作者：

Pariante, Carmine M. ^{[2
]}

Lightman, Stafford L. ^{[1
]}

机构：

[1] Univ Bristol, Henry Wellcome Labs Integrat Neurosci & Endocrino, Bristol BS1 3NY, Avon, England

[2] Kings Coll London, Inst Psychiat, Div Psychol Med & Psychiat, Ctr Cellular Basis Behav,James Black Ctr, London SE5 9NU, England

来源：

TRENDS IN NEUROSCIENCES | 2008年 / 31卷 / 09期

基金：

英国医学研究理事会; 英国生物技术与生命科学研究理事会; 英国惠康基金;

关键词：

D O I：

10.1016/j.tins.2008.06.006

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Studies over the last 40 years have demonstrated that hyperactivity of the hypothalamic-pituitary-adrenal axis is one of the most consistent biological findings in major depression psychiatry, but the mechanisms underlying this abnormality are still unclear.

引用

页码：464 / 468

页数：5

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