Potential Oxidative Stress of Gold Nanoparticles by Induced-NO Releasing in Serum

被引：192

作者：

Jia, Hong Ying ^{[1
]}

Liu, Yang ^{[1
]}

Zhang, Xue Ji ^{[2
]}

Han, Lu ^{[1
]}

Du, Li Bo ^{[1
]}

Tian, Qiu ^{[1
]}

Xut, Yuan Chao ^{[1
]}

机构：

[1] Chinese Acad Sci, State Key Lab Struct Chem Unstable & Stable Speci, Ctr Mol Sci, Inst Chem, Beijing 100190, Peoples R China

[2] Univ S Florida, Dept Chem, Tampa, FL 33620 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 01期

基金：

中国国家自然科学基金;

关键词：

NITRIC-OXIDE; S-NITROSOTHIOLS; BIOCOMPATIBILITY; PEROXYNITRITE; DECOMPOSITION; CYTOTOXICITY; MOLECULES; CHEMISTRY; SENSOR; DAMAGE;

D O I：

10.1021/ja808033w

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Nitric oxide (NO)-release in blood serum initiated by gold nanoparticles has been prove to be a reaction between RSNO and the gold nanoparitctes. In this reaction the NO production was catalyzed on the surface of the nanoparticles, and a new bond of Au-thiolate was simultaneously formed.

引用

收藏

页码：40 / +

页数：3

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