Ionic liquid promoted one-pot synthesis of 3-aminoimidazo[1,2-a]pyridines

被引：143

作者：

Shaabani, A ^{[1
]}

Soleimani, E ^{[1
]}

Maleki, A ^{[1
]}

机构：

[1] Shahid Beheshti Univ, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 18期

关键词：

imidazo[1,2-a]pyridine; ionic liquid; isocyanide; multicomponent reactions; bmim]Br;

D O I：

10.1016/j.tetlet.2006.03.011

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Aminoimidazo[1,2-a]pyridines have been synthesized in good to excellent yields in the presence of the ionic liquid 1-butyl-3-methylimidazolium bromide [brnim]Br, the reaction workup is simple and the ionic liquid can be easily separated from the product and reused. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3031 / 3034

页数：4

共 41 条

[1] Bienaymé H, 1998, ANGEW CHEM INT EDIT, V37, P2234, DOI 10.1002/(SICI)1521-3773(19980904)37:16<2234::AID-ANIE2234>3.0.CO
[2] 2-R
[3] Parallel synthesis of 3-aminoimidazo[1,2-a]pyridines and pyrazines by a new three-component condensation
Blackburn, C
Guan, B
Fleming, P
Shiosaki, K
Tsai, S
[J]. TETRAHEDRON LETTERS, 1998, 39 (22) : 3635 - 3638
[4] A three-component solid-phase synthesis of 3-aminoimidazo[1,2-a]azines
Blackburn, C
[J]. TETRAHEDRON LETTERS, 1998, 39 (31) : 5469 - 5472
[5] Blewitt W. L., 1977, SPECIAL TOPICS HETER, P117
[6] Ionic liquids. Green solvents for the future
Earle, MJ
Seddon, KR
[J]. PURE AND APPLIED CHEMISTRY, 2000, 72 (07) : 1391 - 1398
[7] SYNTHESIS AND ANTIVIRAL ACTIVITY OF 3-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES
ELHAKMAOUI, A
GUEIFFIER, A
MILHAVET, JC
BLACHE, Y
CHAPAT, JP
CHAVIGNON, O
TEULADE, JC
SNOECK, R
ANDREI, G
DECLERCQ, E
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4 (16) : 1937 - 1940
[8] Synthesis of imidazo[1,2-a] annulated pyridines, pyrazines and pyrimidines by a novel three-component condensation
Groebke, K
Weber, L
Mehlin, F
[J]. SYNLETT, 1998, (06) : 661 - +
[9] Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents
Gueiffier, A
Lhassani, M
Elhakmaoui, A
Snoeck, R
Andrei, G
Chavignon, O
Teulade, JC
Kerbal, A
Essassi, EM
Debouzy, JC
Witvrouw, M
Blache, Y
Balzarini, J
DeClercq, E
Chapat, JP
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (14) : 2856 - 2859
[10] Synthesis of imidazo[1,2-a]pyridines as antiviral agents
Gueiffier, A
Mavel, S
Lhassani, M
Elhakmaoui, A
Snoeck, R
Andrei, G
Chavignon, O
Teulade, JC
Witvrouw, M
Balzarini, J
De Clercq, E
Chapat, JP
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (25) : 5108 - 5112

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