Electropolymerized molecularly imprinted polymers as receptor layers in a capacitive chemical sensors

被引：226

作者：

Panasyuk, TL

Mirsky, VM ^{[1
]}

Piletsky, SA

Wolfbeis, OS

机构：

[1] Univ Regensburg, Inst Analyt Chem Chemo & Biosensors, D-93040 Regensburg, Germany

[2] Inst Mol Biol & Genet, UA-252143 Kiev, Ukraine

来源：

ANALYTICAL CHEMISTRY | 1999年 / 71卷 / 20期

关键词：

D O I：

10.1021/ac9903196

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The first application of molecularly imprinted polymers to:chemical sensors with capacitive detection is described. The sensitive layer was prepared by electropolymerization of phenol on gold electrodes in the presence of the template (phenylalanine). The insulating properties of the polymer layer were studied by electrochemical impedance spectroscopy. Electrical leakages through the polymer layer were suppressed by deposition of a self-assembled monolayer of mercaptophenol before polymerization and of alkanethiol after polymerization. At the final stage of sensor preparation, the template was removed. The multilayer system obtained displayed a decrease in electrical capacitance on addition of phenylalanine. Only a low response was observed toward other amino acids and phenol.

引用

页码：4609 / 4613

页数：5

共 24 条

[11] Capacitive monitoring of protein immobilization and antigen-antibody reactions on monomolecular alkylthiol films on gold electrodes [J].