Microwave assisted, highly efficient solid state N- and S-alkylation

被引：12

作者：

Jaisinghani, HG ^{[1
]}

Khadilkar, BM ^{[1
]}

机构：

[1] Univ Bombay, Dept Chem Technol, Bombay 400019, Maharashtra, India

来源：

SYNTHETIC COMMUNICATIONS | 1999年 / 29卷 / 21期

关键词：

D O I：

10.1080/00397919908086007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Secondary amines and thiophenols were alkylated with alkyl and benzyl halides rapidly on alumina supported potassium carbonate under solvent-free conditions using microwaves. Equimolar amounts of the secondary amine/thiophenol and alkyl halide were used. The procedure neither required any strong base nor a PTC. Aniline was also monobenzylated with benzylchloride. Separation of the products from the reactants was very simple by using a nonpolar solvent for desorption.

引用

页码：3693 / 3698

页数：6

共 32 条

[1]

ABENHAIM D, 1994, HETEROCYCLES, V38, P793

[2] GAS-LIQUID PHASE-TRANSFER SYNTHESIS OF PHENYL ETHERS AND SULFIDES WITH CARBONATE AS BASE AND CARBOWAX AS CATALYST [J].

ANGELETTI, E ;

TUNDO, P ;

VENTURELLO, P .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1982, (05) :1137-1141

[3]

[Anonymous], 1993, ORGANIC CHEM USING C

[4]

ARESHIDZE KI, 1976, NEFTEKHIMIYA, P898

[5]

BARTULIN J, 1987, J CHEM SOC P2, V12, P1881

[6] New synthesis method of N-alkylation of carbazole under microwave irradiation in dry media. [J].

Bogdal, D ;

Pielichowski, J ;

Jaskot, K .

SYNTHETIC COMMUNICATIONS, 1997, 27 (09) :1553-1560

[7] Remarkable fast n-alkylation of azaheterocycles under microwave irradiation in dry media [J].

Bogdal, D ;

Pielichowski, J ;

Jaskot, K .

HETEROCYCLES, 1997, 45 (04) :715-722

[8]

BRAM G, 1992, SOLID SUPPORTS CATAL, P302

[9] MICROWAVE-ASSISTED ORGANIC-REACTIONS [J].

CADDICK, S .

TETRAHEDRON, 1995, 51 (38) :10403-10432

[10]

Clark J.H., 1994, CATALYSIS ORGANIC RE

← 1 2 3 4 →