In vivo selection of fluoroquinolone-resistant Escherichia coli isolates expressing plasmid-mediated quinolone resistance and expanded-spectrum β-lactamase

被引：74

作者：

Poirel, L

Pitout, JDD

Calvo, L

Rodriguez-Martinez, JM

Church, D

Nordmann, P

机构：

[1] Univ Paris 11, Fac Med Paris Sud, Hop Bicetre, Assistance Publ Hop Paris,Serv Bacteriol Virol, F-94275 Le Kremlin Bicetre, France

[2] Univ Calgary, Div Microbiol, Calgary Lab Serv, Calgary, AB, Canada

[3] Univ Calgary, Dept Pathol & Lab Med, Calgary, AB, Canada

[4] Univ Calgary, Dept Microbiol & Infect Dis, Calgary, AB, Canada

[5] Univ Calgary, Dept Med, Calgary, AB, Canada

[6] Univ Sevilla, Univ Hosp Virgen Macarena, Seville, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 04期

关键词：

D O I：

10.1128/AAC.50.4.1525-1527.2006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A ciprofloxacin-resistant Escherichia coli isolate, isolate 1B, was obtained from a urinary specimen of a Canadian patient treated with norfloxacin for infection due to a ciprofloxacin-susceptible isolate, isolate 1A. Both isolates harbored a plasmid-encoded sul1-type integron with qnrA1 and bla(VEB-1) genes. Isolate 1B had amino acid substitutions in gyrase and topoisomerase.

引用

页码：1525 / 1527

页数：3

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