Positron emission tomography neuroreceptor imaging as a tool in drug discovery, research and development

被引:46
作者
Burns, HD [1 ]
Hamill, TG [1 ]
Eng, W [1 ]
Francis, B [1 ]
Fioravanti, C [1 ]
Gibson, RE [1 ]
机构
[1] Merck Res Labs, Dept Pharmacol, West Point, PA 19438 USA
关键词
D O I
10.1016/S1367-5931(99)80059-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Improved communication and cooperation between research-driven drug companies and academic positron emmision tomography (PET) centers, coupled with improvements in PET camera resolution, the availability of small animal PET cameras and a growing list of neuroreceptor-specific PET tracers, have all-contributed to a substantial increase in the use and value of PET as a tool in central nervous system drug discovery and development.
引用
收藏
页码:388 / 394
页数:7
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