Mechanism of cell-cell adhesion complex assembly

被引:87
作者
Troyanovsky, SM [1 ]
机构
[1] Washington Univ, Sch Med, Div Dermatol, St Louis, MO 63110 USA
关键词
D O I
10.1016/S0955-0674(99)00021-6
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Cell-cell adhesion complexes play an important role in the organization and behavior of cells in tissues. An important step in the formation of such complexes is the clustering of the adhesion receptors; this is critical for proper adhesion, for anchorage of the cytoskeleton to the plasma membrane, and for generation of different intracellular signals. Recent advances reveal that several interconnected mechanisms are responsible for clustering of the different adhesion receptors.
引用
收藏
页码:561 / 566
页数:6
相关论文
共 71 条
[31]   Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins [J].
Litvinov, SV ;
Balzar, M ;
Winter, MJ ;
Bakker, HAM ;
BriairedeBruijn, I ;
Prins, F ;
Fleuren, GJ ;
Warnaar, SO .
JOURNAL OF CELL BIOLOGY, 1997, 139 (05) :1337-1348
[32]   Mutations in the plakophilin 1 gene result in ectodermal dysplasia skin fragility syndrome [J].
McGrath, JA ;
McMillan, JR ;
Shemanko, CS ;
Runswick, SK ;
Leight, IM ;
Lane, EB ;
Garrod, DR ;
Eady, RAJ .
NATURE GENETICS, 1997, 17 (02) :240-244
[33]   Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands [J].
Morita, K ;
Furuse, M ;
Fujimoto, K ;
Tsukita, S .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (02) :511-516
[34]   Structural basis of calcium-induced E-cadherin rigidification and dimerization [J].
Nagar, B ;
Overduin, M ;
Ikura, M ;
Rini, JM .
NATURE, 1996, 380 (6572) :360-364
[35]  
Nieman MT, 1999, J CELL SCI, V112, P1621
[36]  
Nieset JE, 1997, J CELL SCI, V110, P1013
[37]  
Noë V, 1999, J CELL SCI, V112, P127
[38]   LOCALIZATION OF SPECIFICITY DETERMINING SITES IN CADHERIN CELL-ADHESION MOLECULES [J].
NOSE, A ;
TSUJI, K ;
TAKEICHI, M .
CELL, 1990, 61 (01) :147-155
[39]   Cell-junctional and cytoskeletal organization in mouse blastocysts lacking E-cadherin [J].
Ohsugi, M ;
Larue, L ;
Schwarz, H ;
Kemler, R .
DEVELOPMENTAL BIOLOGY, 1997, 185 (02) :261-271