Gold-catalyzed synthesis of 1,3-disubstituted benzenes through tandem allylation/cyclization reaction of alkynals

被引：17

作者：

Bhunia, Sabyasachi ^{[1
]}

Abu Sohel, Shariar Md. ^{[1
]}

Yang, Chao-Chin ^{[1
]}

Lush, Shie-Fu ^{[2
]}

Shen, Fwu-Ming ^{[3
]}

Liu, Rai-Shung ^{[1
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 30043, Taiwan

[2] Yuan Pei Univ, Dept Biotechnol, Hsinchu, Taiwan

[3] Yuan Pei Univ, Dept Med Lab Sci & Biotechnol, Hsinchu, Taiwan

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2009年 / 694卷 / 04期

关键词：

Allylation; Alkynal; Benzenes; Catalysis; Tandem reaction; CYCLOISOMERIZATION REACTIONS; SKELETAL REORGANIZATION; PLATINUM; ENYNES; CYCLIZATION; 1,5-ENYNES; BENZANNULATION; ACCESS; REARRANGEMENTS; ISOMERIZATION;

D O I：

10.1016/j.jorganchem.2008.10.049

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Treatment of alkynals with 2-substituted allylsilanes and PPh3AuCl/AgOTf (5/3 mol%) catalyst led to formation of 1,3-disubstituted benzenes efficiently. This reaction sequence comprises an initial allylation of aldehyde, followed by cycloisomerization of enynes; PPh3AuOTf is active in both steps. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：566 / 570

页数：5

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