Towards the synthesis of pyloricidins:: synthesis of (2S,3R,4R,5S)-5-(tert-butyloxycarbonyl)amino-2,3,4,6-tetrahydroxyhexanoyl-β-D-phenylalanine methyl ester

被引：6

作者：

Chandrasekhar, S ^{[1
]}

Babu, BN ^{[1
]}

Reddy, NR ^{[1
]}

Chandraiah, L ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

ARKIVOC | 2005年

关键词：

amino acids; antibiotic; dihydroxylation; homologation; debenzylation;

D O I：

10.3998/ark.5550190.0006.b06

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly practical and efficient synthesis of (2S, 3R, 4R, 5S)-5-(tert-butyloxycarbonyl) amino2,3,4,6-tetrahydroxyhexanoyl- beta-D-phenylalanine methyl ester was achieved using easily available Garner aldehyde and phenylglycine, which is an advanced intermediate for the synthesis of pyloricidins.

引用

页码：40 / 47

页数：8

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