A facile synthesis of 1,7-dicarbonyl compounds via three-component Michael addition reactions

被引:53
作者
Chetia, A [1 ]
Saikia, CJ [1 ]
Lekhok, KC [1 ]
Boruah, RC [1 ]
机构
[1] Reg Res Lab, Div Med Chem, Jorhat 785006, Assam, India
关键词
1,7-dicarbonyl; three-component; Michael addition; nitromethane; alpha; beta-unsaturated carbonyl compounds;
D O I
10.1016/j.tetlet.2004.01.137
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A convenient one-pot synthesis of 1,7-dicarbonyl compounds has been accomplished by a three-component Michael addition reaction of nitromethane with two unsymmetric alpha,beta-unsaturated carbonyl compounds in the presence of a base. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2649 / 2651
页数:3
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