Sperm guidance in mammals - an unpaved road to the egg

被引:407
作者
Eisenbach, M [1 ]
Giojalas, LC
机构
[1] Weizmann Inst Sci, Dept Biol Chem, IL-76100 Rehovot, Israel
[2] Univ Nacl Cordoba, Ctr Cell & Mol Biol, Fac Sci, RA-5000 Cordoba, Argentina
关键词
D O I
10.1038/nrm1893
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Contrary to the prevalent view, there seems to be no competition in the mammalian female genital tract among large numbers of sperm cells that are racing towards the egg. Instead, small numbers of the ejaculated sperm cells enter the Fallopian tube, and these few must be guided to make the remaining long, obstructed way to the egg. Here, we review the mechanisms by which mammalian sperm cells are guided to the egg.
引用
收藏
页码:276 / 285
页数:10
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