Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016)

被引：8

作者：

Kryshtafovych, Andriy ^{[1
]}

Albrecht, Reinhard ^{[2
]}

Basle, Arnaud ^{[3
]}

Bule, Pedro ^{[4
]}

Caputo, Alessandro T. ^{[5
]}

Carvalho, Ana Luisa ^{[6
]}

Chao, Kinlin L. ^{[7
]}

Diskin, Ron ^{[8
]}

Fidelis, Krzysztof ^{[1
]}

Fontes, Carlos M. G. A. ^{[4
]}

Fredslund, Folmer ^{[9
]}

Gilbert, Harry J. ^{[3
]}

Goulding, Celia W. ^{[10
]}

Hartmann, Marcus D. ^{[2
]}

Hayes, Christopher S. ^{[11
]}

Herzberg, Osnat ^{[7
,12
]}

Hill, Johan C. ^{[5
]}

Joachimiak, Andrzej ^{[13
,14
]}

Kohring, Gert-Wieland ^{[15
]}

Koning, Roman I. ^{[16
,17
]}

Lo Leggio, Leila ^{[9
]}

Mangiagalli, Marco ^{[18
]}

Michalska, Karolina ^{[13
]}

Moult, John ^{[19
]}

Najmudin, Shabir ^{[4
]}

Nardini, Marco ^{[20
]}

Nardone, Valentina ^{[20
]}

Ndeh, Didier ^{[3
]}

Thanh-Hong Nguyen ^{[21
]}

Pintacuda, Guido ^{[22
]}

Postel, Sandra ^{[23
]}

van Raaij, Mark J. ^{[21
]}

Roversi, Pietro ^{[5
,24
]}

Shimon, Amir ^{[8
]}

Singh, Abhimanyu K. ^{[25
]}

Sundberg, Eric J. ^{[26
,27
]}

Tars, Kaspars ^{[28
,29
]}

Zitzmann, Nicole ^{[5
]}

Schwede, Torsten ^{[30
]}

机构：

[1] Univ Calif Davis, Genome Ctr, 451 Hlth Sci Dr, Davis, CA 95616 USA

[2] Max Planck Inst Dev Biol, Dept Prot Evolut, D-72076 Tubingen, Germany

[3] Univ Newcastle, Inst Cell & Mol Biosci, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

[4] Univ Lisbon, CIISA Fac Med Vet, Ave Univ Tecn, P-1300477 Lisbon, Portugal

[5] Univ Oxford, Oxford Glycobiol Inst, Dept Biochem, South Parks Rd, Oxford OX1 3QU, England

[6] Univ Nova Lisboa, Dept Quim, UCIBIO, REQUIMTE,Fac Ciencias & Tecnol, P-2829516 Caparica, Portugal

[7] Univ Maryland, Inst Biosci & Biotechnol Res, Rockville, MD 20850 USA

[8] Weizmann Inst Sci, Dept Biol Struct, Rehovot, Israel

[9] Univ Copenhagen, Dept Chem, Univ Pk 5, DK-2100 Copenhagen O, Denmark

[10] Univ Calif Irvine, Dept Mol Biol & Biochem Pharmaceut Sci, Irvine, CA 92697 USA

[11] Univ Calif Santa Barbara, Biomol Sci & Engn Program, Dept Mol Cellular & Dev Biol, Santa Barbara, CA 93106 USA

[12] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA

[13] Argonne Natl Lab, Biosci Div, Midwest Ctr Struct Genom, Struct Biol Ctr, 9700 S Cass Ave, Argonne, IL 60439 USA

[14] Univ Chicago, Dept Biochem & Mol Biol, 920 E 58Th St, Chicago, IL 60637 USA

[15] Saarland Univ, Microbiol, Campus Bldg A1-5, D-66123 Saarbrucken, Saarland, Germany

[16] Leiden Univ, Inst Biol Leiden, Netherlands Ctr Electron Nanoscopy, NL-2333 CC Leiden, Netherlands

[17] Leiden Univ, Dept Mol Cell Biol, Med Ctr, NL-2300 RC Leiden, Netherlands

[18] Univ Milano Bicocca, Dept Biosci & Biotechnol, I-20126 Milan, Italy

[19] Univ Maryland, Dept Mol Genet & Cell Biol, Inst Biosci & Biotechnol Res, 9600 Gudelsky Dr, Rockville, MD 20850 USA

[20] Univ Milan, Dept Biosci, I-20133 Milan, Italy

[21] CSIC, Dept Macromol Struct, Ctr Nacl Biotecnol, Calle Darwin 3, Madrid 28049, Spain

[22] UCB Lyon 1, Ctr RMN Tres Hauts Champs, ENS Lyon,Univ Lyon,CNRS,UMR 5280, Inst Sci Analyt, F-69100 Villeurbanne, France

[23] Univ Maryland, Inst Human Virol, Sch Med, Baltimore, MD 21201 USA

[24] Univ Leicester, Leicester Inst Struct & Chem Biol, Dept Mol & Cell Biol, Henry Wellcome Bldg,Univ Rd, Leicester LE1 7RN, Leics, England

[25] Univ Kent, Sch Biosci, Canterbury CT2 7NJ, Kent, England

[26] Univ Maryland, Sch Med, Dept Med, Inst Human Virol, Baltimore, MD 21201 USA

[27] Univ Maryland, Sch Med, Dept Microbiol & Immunol, Inst Human Virol, Baltimore, MD 21201 USA

[28] Latvian Biomed Res & Study Ctr, Ratsupites 1, LV-1067 Riga, Latvia

[29] Univ Latvia, Dept Mol Biol, Fac Biol, Jelgavas 1, LV-1004 Riga, Latvia

[30] SIB, Biozentrum, Klingelbergstr 50, CH-4056 Basel, Switzerland

来源：

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS | 2018年 / 86卷

基金：

英国惠康基金; 美国国家卫生研究院; 以色列科学基金会;

关键词：

CASP; NMR; protein structure prediction; X-ray crystallography; GLUCOSE-GLYCOPROTEIN GLUCOSYLTRANSFERASE; GROWTH-INHIBITION CDI; PARALLEL BETA-HELICES; FLAGELLAR CAP PROTEIN; CRYSTAL-STRUCTURE; STRUCTURAL BASIS; 3-DIMENSIONAL STRUCTURE; PSEUDOMONAS-AERUGINOSA; RHAMNOGALACTURONAN-II; CYTOTOXIC DOMAIN;

D O I：

10.1002/prot.25392

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The functional and biological significance of the selected CASP12 targets are described by the authors of the structures. The crystallographers discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP12 experiment.

引用

页码：27 / 50

页数：24

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