Elementary arithmetic operations by enzymes: A model for metabolic pathway based computing

被引：169

作者：

Baron, R ^{[1
]}

Lioubashevski, O ^{[1
]}

Katz, E ^{[1
]}

Niazov, T ^{[1
]}

Willner, I ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 10期

关键词：

enzymes; logic gates; metabolism; redox chemistry;

D O I：

10.1002/anie.200503314

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Physio-logical: A system of four enzymes, horseradish peroxidase, glucose dehydrogenase, glucose oxidase, and catalase, operate in parallel in the presence of NADH and NAD+ to yield AND and XOR gates (see picture). Glucose and H2O2 act as the inputs, and the absorbance that follows the production of gluconic acid or NADH provide the outputs of the AND and XOR gates, respectively. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1572 / 1576

页数：5

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