RETRACTED: Development of functional hydrogels for heart failure (Retracted article. See vol. 9, pg. 3412, 2021)

被引:24
作者
Han, Yanxin [1 ]
Yang, Wenbo [1 ]
Cui, Wenguo [2 ]
Yang, Ke [1 ]
Wang, Xiaoqun [1 ]
Chen, Yanjia [1 ]
Deng, Lianfu [2 ]
Zhao, Yuanjin [2 ,3 ]
Jin, Wei [1 ]
机构
[1] Shanghai Jiao Tong Univ, Dept Cardiol, Inst Cardiovasc Dis, Ruijin Hosp,Sch Med, 197 Ruijin Er Rd, Shanghai 200025, Peoples R China
[2] Shanghai Jiao Tong Univ, Shanghai Key Lab Prevent & Treatment Bone & Joint, Shanghai Inst Traumatol & Orthopaed, Ruijin Hosp,Sch Med, 197 Ruijin 2nd Rd, Shanghai 200025, Peoples R China
[3] Southeast Univ, State Key Lab Bioelect, Sch Biol Sci & Med Engn, Nanjing 210096, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
LEFT-VENTRICULAR FUNCTION; PLURIPOTENT STEM-CELLS; ENDOTHELIAL PROGENITOR CELLS; FIBROBLAST-GROWTH-FACTOR; MYOCARDIAL-INFARCTION; SUSTAINED-RELEASE; CARDIAC-FUNCTION; INJECTABLE HYDROGELS; MATRIX METALLOPROTEINASES; ISCHEMIC-MYOCARDIUM;
D O I
10.1039/c8tb02591f
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
082905 [生物质能源与材料]; 100103 [病原生物学];
摘要
Although some advanced treatments of heart failure (HF) have experienced great development in recent decades, morbidity and mortality associated with HF have not improved significantly. Hydrogels have some unique advantages for the delivery and controlled release of bioactive molecules, drugs, and cells, which can directly affect the heart locally. Many studies have shown that hydrogels represent a new approach for the treatment of HF. In this review, we present a current perspective of hydrogel-based approaches for cardiac tissue engineering and myocardial regeneration in ischemia-induced HF, with an emphasis on functional studies, translation, and clinical advancements.
引用
收藏
页码:1563 / 1580
页数:18
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