The role of flow in green chemistry and engineering

被引:466
作者
Newman, Stephen G. [1 ]
Jensen, Klavs F. [1 ]
机构
[1] MIT, Dept Chem Engn, Cambridge, MA 02139 USA
基金
加拿大自然科学与工程研究理事会;
关键词
SUPERCRITICAL CARBON-DIOXIDE; CONTINUOUS PHOTOOXIDATION; PHOTOREDOX CATALYSIS; SELECTIVE OXIDATION; LIQUID-EXTRACTION; ORGANIC-SYNTHESIS; REACTION-KINETICS; SINGLET OXYGEN; HECK REACTION; HIGH-PRESSURE;
D O I
10.1039/c3gc40374b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Flow chemistry and continuous processing can offer many ways to make synthesis a more sustainable practice. These technologies help bridge the large gap between academic and industrial settings by often providing a more reproducible, scalable, safe and efficient option for performing chemical reactions. In this review, we use selected examples to demonstrate how continuous methods of synthesis can be greener than batch synthesis on a small and a large scale.
引用
收藏
页码:1456 / 1472
页数:17
相关论文
共 135 条
[1]   Sequential Reaction-Separation in a Microchannel Reactor for Liquid-Liquid Phase Transfer Catalysis [J].
Aljbour, Salah ;
Yamada, Hiroshi ;
Tagawa, Tomohiko .
TOPICS IN CATALYSIS, 2010, 53 (7-10) :694-699
[2]   Origins, current status, and future challenges of green chemistry [J].
Anastas, PT ;
Kirchhoff, MM .
ACCOUNTS OF CHEMICAL RESEARCH, 2002, 35 (09) :686-694
[3]   Design through the 12 principles of green engineering [J].
Anastas, PT ;
Zimmerman, JB .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2003, 37 (05) :94A-101A
[4]   Using Continuous Processes to Increase Production [J].
Anderson, Neal G. .
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2012, 16 (05) :852-869
[5]   Continuous multi-injection reactor for multipurpose production - Part I [J].
Barthe, Philippe ;
Guermeur, Celine ;
Lobet, Olivier ;
Moreno, Maxime ;
Woehl, Pierre ;
Roberge, Dominique M. ;
Bieler, Nikolaus ;
Zimmermann, Bertin .
CHEMICAL ENGINEERING & TECHNOLOGY, 2008, 31 (08) :1146-1154
[6]   The use of diethylaminosulfur trifluoride (DAST) for fluorination in a continuous-flow microreactor [J].
Baumann, Marcus ;
Baxendale, Ian R. ;
Ley, Steven V. .
SYNLETT, 2008, (14) :2111-2114
[7]   Development of fluorination methods using continuous-flow microreactors [J].
Baumann, Marcus ;
Baxendale, Ian R. ;
Martin, Laetitia J. ;
Ley, Steven V. .
TETRAHEDRON, 2009, 65 (33) :6611-6625
[8]   Substantial rate enhancements of the esterification reaction of phthalic anhydride with methanol at high pressure and using supercritical CO2 as a co-solvent in a glass microreactor [J].
Benito-Lopez, F. ;
Tiggelaar, R. M. ;
Salbut, K. ;
Huskens, J. ;
Egberink, R. J. M. ;
Reinhoudt, D. N. ;
Gardeniers, H. J. G. E. ;
Verboom, W. .
LAB ON A CHIP, 2007, 7 (10) :1345-1351
[9]   Optical fiber-based on-line UV/Vis spectroscopic monitoring of chemical reaction kinetics under high pressure in a capillary microreactor [J].
Benito-Lopez, F ;
Verboom, W ;
Kakuta, M ;
Gardeniers, JGE ;
Egberink, RJM ;
Oosterbroek, ER ;
van den Berg, A ;
Reinhoudt, DN .
CHEMICAL COMMUNICATIONS, 2005, (22) :2857-2859
[10]   Cleaner Continuous Photo-Oxidation Using Singlet Oxygen in Supercritical Carbon Dioxide [J].
Bourne, Richard A. ;
Han, Xue ;
Poliakoff, Martyn ;
George, Michael W. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (29) :5322-5325