Problems related to short-term antihypertensive therapy in acute ischemic stroke

被引：4

作者：

Semplicini, A ^{[1
]}

Benetton, V ^{[1
]}

Mascagna, V ^{[1
]}

Macchini, L ^{[1
]}

Realdi, A ^{[1
]}

Sartori, M ^{[1
]}

Caló, L ^{[1
]}

机构：

[1] Univ Padua, Sch Med, Clin Med 4, Dept Clin & Expt Med, Padua, Italy

来源：

CLINICAL AND EXPERIMENTAL HYPERTENSION | 2006年 / 28卷 / 3-4期

关键词：

blood pressure; cerebral infarction; treatment outcome;

D O I：

10.1080/10641960600549421

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Hypertension is a common early finding after an acute ischemic stroke, even in previously normotensive patients. But its significance and proper management are a matter of debate. because of the lack of adequately powered randomized clinical trials. A close analysis of observational and interventional trials, published so far, fails to convince that an early antihypertensive therapy is needed and beneficial. During the first 24-48 hr after ischemic stroke, only blood pressure values repeatedly, higher than 220/120 mmHg require antihypertensive treatment to keel) blood pressure levels in the range of 180-220 mmHg systolic and 100-120 diastolic. Blood pressure reduction should be cautious with the aim of keeping the pressure at relatively high values (180/100-105 in previously hypertensive patients and 160-180/90-100 in previously normotensive patients). The usefulness of increasing blood pressure with vasopressive agents in selected patients with ischemic stroke deserves adequate testing with randomized clinical trials.

引用

页码：327 / 334

页数：8

共 42 条

[11] Stroke precipitated dy moderate blood pressure reduction [J].