Regiospecific acylation of acetals.: A convenient method to obtain β-methoxyvinyl trichloromethyl ketones

被引：69

作者：

Martins, MAP ^{[1
]}

Bastos, GP

Bonacorso, HG

Zanatta, N

Flores, AFC

Siqueira, GM

机构：

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

[2] Univ Fed Pelotas, Dept Quim Organ, BR-96040160 Pelotas, RS, Brazil

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 23期

关键词：

D O I：

10.1016/S0040-4039(99)00672-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The regiochemistry of the acylation of enol ethers, generated in situ, from acetals of unsymmetrical ketones is reported. These results demonstrate a convenient one-pot method to obtain a series of beta-methoxyvinyl trichloromethyl ketones [CCl3COCH=C(OMe)R, where R=Et, n-Bu, i-Pr, (CH2)(2)C(OMe)=CHC(O)CCl3 and (CH2)(5)CO2CH3)] in high yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：4309 / 4312

页数：4

共 28 条

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