Selection for Loss of RpoS in Cronobacter sakazakii by Growth in the Presence of Acetate as a Carbon Source

被引:10
作者
Alvarez-Ordonez, Avelino [1 ,2 ]
Begley, Maire [1 ,2 ]
Hill, Colin [1 ,2 ,3 ]
机构
[1] Natl Univ Ireland Univ Coll Cork, Dept Microbiol, Cork, Ireland
[2] Natl Univ Ireland Univ Coll Cork, Food Hlth Ireland, Cork, Ireland
[3] Natl Univ Ireland Univ Coll Cork, Alimentary Pharmabiot Ctr, Cork, Ireland
关键词
ENTEROBACTER-SAKAZAKII; RESISTANCE; TOLERANCE; SURVIVAL;
D O I
10.1128/AEM.03302-12
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
We demonstrate that growth of Cronobacter sakazakii in the presence of acetate as a carbon source promotes loss of RpoS, with a consequent reduction in stress tolerance. This suggests that C. sakazakii is capable of regulating cell fitness through mutation of the rpoS gene.
引用
收藏
页码:2099 / 2102
页数:4
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