DNA microarrays for malaria

被引：46

作者：

Rathod, PK ^{[1
]}

Ganesan, K

Hayward, RE

Bozdech, Z

DeRisi, JL

机构：

[1] Univ Washington, Dept Chem, Seattle, WA 98195 USA

[2] NIAID, Parasit Dis Lab, NIH, Bethesda, MD 20892 USA

[3] Univ Calif San Francisco, Dept Biochem, San Francisco, CA 94143 USA

来源：

TRENDS IN PARASITOLOGY | 2002年 / 18卷 / 01期

关键词：

D O I：

10.1016/S1471-4922(01)02153-5

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

DNA microarrays are a powerful tool for the analysis of RNA and DNA composition on a whole-genome scale. The first applications of this technology in parasitology are in place. This review examines the various approaches to Plasmodium transcript-profiling that are being adopted using DNA microarray analysis and discusses additional strategies for obtaining and collating information relevant to the search for drug and vaccine candidates in malaria.

引用

页码：39 / 45

页数：7

共 53 条

[51] A novel class of supercoil-independent nuclease hypersensitive site is comprised of alternative DNA structures that flank eukaryotic genes [J].