Luminescent Chemodosimeters for Bioimaging

被引:2149
作者
Yang, Yuming [1 ,2 ,3 ]
Zhao, Qiang [4 ,5 ]
Feng, Wei [1 ,2 ,3 ]
Li, Fuyou [1 ,2 ,3 ]
机构
[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
[2] Fudan Univ, State Key Lab Mol Engn Polymers, Shanghai 200433, Peoples R China
[3] Fudan Univ, Inst Biomed Sci, Shanghai 200433, Peoples R China
[4] Nanjing Univ Posts & Telecommun, KLOEID, Nanjing 210046, Jiangsu, Peoples R China
[5] Nanjing Univ Posts & Telecommun, IAM, Nanjing 210046, Jiangsu, Peoples R China
关键词
TURN-ON FLUORESCENT; RHODAMINE-BASED FLUORESCENT; UP-CONVERSION LUMINESCENCE; IMAGING HYDROGEN-PEROXIDE; SELECTIVE PHOSPHORESCENT CHEMODOSIMETER; FLOW-INJECTION SPECTROFLUOROMETRY; CATIONIC IRIDIUM(III) COMPLEXES; OPTICAL-ELECTROCHEMICAL SENSOR; PHOTOINDUCED ELECTRON-TRANSFER; HISTIDINE-RICH GLYCOPROTEIN;
D O I
10.1021/cr2004103
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Chemodosimeters in luminescence bioimaging have attracted increasing attention and become a very active research field because of their rapid response, high sensitivity, and excellent selectivity. Chemodosimeters are used to detect a target analyte through a usually irreversible chemical reaction between the dosimeter molecule and the analyte. Hence, the selectivity of chemodosimeters for the target analyte is often very high. Luminescent chemodosimeters provide a useful alternative to chemosensors for detecting analytes in biological systems, especially for detecting heavy-metal cations, which often cause luminescence quenching in chemosensor systems. The most reported luminescent chemodosimeters have been based on fluorescence turn-on, or emission wavelength shifts, which makes them ideal for application in bioimaging. Besides molecular design, it is also important to understand better the cellular uptake behavior of luminescent chemodosimeters for bioimaging application.
引用
收藏
页码:192 / 270
页数:79
相关论文
共 621 条
[1]   Development of a Highly Sensitive Fluorescence Probe for Hydrogen Peroxide [J].
Abo, Masahiro ;
Urano, Yasuteru ;
Hanaoka, Kenjiro ;
Terai, Takuya ;
Komatsu, Toru ;
Nagano, Tetsuo .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (27) :10629-10637
[2]   An integrated system of pyrene and rhodamine-6G for selective colorimetric and fluorometric sensing of mercury(II) [J].
Ahamed, B. Nisar ;
Ghosh, Pradyut .
INORGANICA CHIMICA ACTA, 2011, 372 (01) :100-107
[3]   Phenothiazine attached Ru(bpy)32+ derivative as highly selective "turn-ON" luminescence chemodosimeter for Cu2+ [J].
Ajayakumar, Gopalakrishnan ;
Sreenath, Kesavapillai ;
Gopidas, Karical R. .
DALTON TRANSACTIONS, 2009, (07) :1180-1186
[4]   A red-emitting naphthofluorescein-based fluorescent probe for selective detection of hydrogen peroxide in living cells [J].
Albers, Aaron E. ;
Dickinson, Bryan C. ;
Miller, Evan W. ;
Chang, Christopher J. .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (22) :5948-5950
[5]   A FRET-based approach to ratiometric fluorescence detection of hydrogen peroxide [J].
Albers, Aaron E. ;
Okreglak, Voytek S. ;
Chang, Christopher J. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (30) :9640-9641
[6]   Oxidative stress in neurodegeneration: cause or consequence? [J].
Andersen, JK .
NATURE MEDICINE, 2004, 10 (07) :S18-S25
[7]   Development and Applications of Fluorogenic Probes for Mercury(II) Based on Vinyl Ether Oxymercuration [J].
Ando, Shin ;
Koide, Kazunori .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (08) :2556-2566
[8]  
[Anonymous], 2010, ANALYST
[9]  
[Anonymous], 2012, Thesis
[10]   Chemical forms of mercury and cadmium accumulated in marine mammals and seabirds as determined by XAFS analysis [J].
Arai, T ;
Ikemoto, T ;
Hokura, A ;
Terada, Y ;
Kunito, T ;
Tanabe, S ;
Nakai, I .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2004, 38 (24) :6468-6474