Two carbon homologation of carboxylic acids using acrylamide as a radical trap

被引：10

作者：

Barton, DHR

Liu, WS

机构：

[1] Department of Chemistry, Texas A and M University, College Station

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 14期

关键词：

D O I：

10.1016/S0040-4039(97)00418-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Photolysis of O-acyl derivatives of N-hydroxy-2-thiopyridone in the presence of acrylamide in dichloromethane furnished crystalline 2-(pyridine-2-thiyl)carboxamides. Desulfurization of the latter by nickel boride afforded primary amides in excellent yields. (C) 1997 Elsevier Science Ltd.

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收藏

页码：2431 / 2434

页数：4

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