Sequence-encoded self-assembly of multiple-nanocomponent arrays by 2D DNA scaffolding

被引:170
作者
Pinto, YY
Le, JD
Seeman, NC
Musier-Forsyth, K
Taton, TA
Kiehl, RA [1 ]
机构
[1] Univ Minnesota, Dept Elect & Comp Engn, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA
[3] NYU, Dept Chem, New York, NY 10003 USA
关键词
D O I
10.1021/nl0515495
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Regular 2D arrays of multiple types of nanocomponents were constructed by self-assembly to DNA scaffolding with alternating rows of sequence-encoded hybridization sites. Different-sized Au particles coated with DNA complementary to one of the sites were bound to the scaffolding, producing alternating rows of the two nanocomponents with a 32-nm inter-row spacing. These results demonstrate the potential for using DNA to self-assemble complex arrays of components with nanometer-scale precision.
引用
收藏
页码:2399 / 2402
页数:4
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