clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

被引：26272

作者：

Yu, Guangchuang ^{[1
]}

Wang, Li-Gen ^{[2
]}

Han, Yanyan ^{[1
]}

He, Qing-Yu ^{[1
]}

机构：

[1] Jinan Univ, Inst Life & Hlth Engn, Key Lab Funct Prot Res, Guangdong Higher Educ Inst, Guangzhou 510632, Guangdong, Peoples R China

[2] Guangdong Informat Ctr, Guangzhou, Guangdong, Peoples R China

来源：

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY | 2012年 / 16卷 / 05期

基金：

中国国家自然科学基金;

关键词：

ONTOLOGY; NETWORKS; SOFTWARE; SYSTEM; TERMS; LISTS;

D O I：

10.1089/omi.2011.0118

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 090105 [作物生产系统与生态工程];

摘要：

Increasing quantitative data generated from transcriptomics and proteomics require integrative strategies for analysis. Here, we present an R package, clusterProfiler that automates the process of biological-term classification and the enrichment analysis of gene clusters. The analysis module and visualization module were combined into a reusable workflow. Currently, clusterProfiler supports three species, including humans, mice, and yeast. Methods provided in this package can be easily extended to other species and ontologies. The clusterProfiler package is released under Artistic-2.0 License within Bioconductor project. The source code and vignette are freely available at http://bioconductor.org/packages/release/bioc/html/clusterProfiler.html

引用

收藏

页码：284 / 287

页数：4

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