A sol-gel derived molecular imprinted luminescent PET sensing material for 2,4-dichlorophenoxyacetic acid

被引:73
作者
Leung, MKP [1 ]
Chow, CF [1 ]
Lam, MHW [1 ]
机构
[1] City Univ Hong Kong, Dept Biol & Chem, Hong Kong, Hong Kong, Peoples R China
关键词
D O I
10.1039/b103182c
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A novel sol-gel derived molecular imprinted luminescent sensing material has been fabricated by a conventional sol-gel process. 2,4-Dichlorophenoxyacetic acid (2,4-D) was used as template for the imprinting process and a tailor-made organosilane, 3-[N,N-bis(9-anthrylmethyl) amino] propyltriethoxysilane (1), was used as the functional monomer. Luminescent properties of 1 were perturbed by acid-base ion-pair formation with 2,4-D leading to suppression of photoinduced electron transfer (PET) quenching of its anthryl fluorophores. Such PET fluorescent response was preserved after the preorganized monomer-template aggregates were cross-linked by a sol-gel process. The resultant sol-gel derived luminescent material was found to selectively respond to 2,4-D in aqueous media at pH 7. Average binding affinity of recognition sites in the material for 2,4-D was estimated to be (2.23 +/- 0.5) x 10(6) M-1. Selectivity of the MIP was also evaluated. The present study demonstrated the feasibility of using a PET mechanism as a means of signal transduction for molecular imprinted polymer (MIP) based luminescent sensing of non-fluorescent analytes.
引用
收藏
页码:2985 / 2991
页数:7
相关论文
共 66 条
  • [21] Molecularly imprinted polymers and their use in biomimetic sensors
    Haupt, K
    Mosbach, K
    [J]. CHEMICAL REVIEWS, 2000, 100 (07) : 2495 - 2504
  • [22] SOME STUDIES OF MOLECULARLY-IMPRINTED POLYMER MEMBRANES IN COMBINATION WITH FIELD-EFFECT DEVICES
    HEDBORG, E
    WINQUIST, F
    LUNDSTROM, I
    ANDERSSON, LI
    MOSBACH, K
    [J]. SENSORS AND ACTUATORS A-PHYSICAL, 1993, 37-8 : 796 - 799
  • [23] Fluorescent saccharide receptors: A sweet solution to the design, assembly and evaluation of boronic acid derived PET sensors
    James, TD
    Linnane, P
    Shinkai, S
    [J]. CHEMICAL COMMUNICATIONS, 1996, (03) : 281 - 288
  • [24] Saccharide sensing with molecular receptors based on boronic acid
    James, TD
    Sandanayake, KRAS
    Shinkai, S
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1996, 35 (17) : 1910 - 1922
  • [25] Polymer-based lanthanide luminescent sensor for detection of the hydrolysis product of the nerve agent Soman in water
    Jenkins, AL
    Uy, OM
    Murray, GM
    [J]. ANALYTICAL CHEMISTRY, 1999, 71 (02) : 373 - 378
  • [26] BIOSENSORS FOR ENVIRONMENTAL-CONTROL
    KARUBE, I
    NOMURA, Y
    ARIKAWA, Y
    [J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 1995, 14 (07) : 295 - 299
  • [27] Molecular imprinting of bulk, microporous silica
    Katz, A
    Davis, ME
    [J]. NATURE, 2000, 403 (6767) : 286 - 289
  • [28] COMPETITIVE AMPEROMETRIC MORPHINE SENSOR-BASED ON AN AGAROSE IMMOBILIZED MOLECULARLY IMPRINTED POLYMER
    KRIZ, D
    MOSBACH, K
    [J]. ANALYTICA CHIMICA ACTA, 1995, 300 (1-3) : 71 - 75
  • [29] Molecular imprinting - New possibilities for sensor technology
    Kriz, D
    Ramstrom, O
    Mosbach, K
    [J]. ANALYTICAL CHEMISTRY, 1997, 69 (11) : A345 - A349
  • [30] INTRODUCING BIOMIMETIC SENSORS BASED ON MOLECULARLY IMPRINTED POLYMERS AS RECOGNITION ELEMENTS
    KRIZ, D
    RAMSTROM, O
    SVENSSON, A
    MOSBACH, K
    [J]. ANALYTICAL CHEMISTRY, 1995, 67 (13) : 2142 - 2144