Oriamide, a new cytotoxic cyclic peptide containing a novel amino acid from the marine sponge Theonella sp.

被引：31

作者：

Chill, L

Kashman, Y

Schleyer, M

机构：

[1] TEL AVIV UNIV,SCH CHEM,IL-69978 TEL AVIV,ISRAEL

[2] OCEANOG RES INST,DURBAN,SOUTH AFRICA

来源：

TETRAHEDRON | 1997年 / 53卷 / 47期

关键词：

D O I：

10.1016/S0040-4020(97)10054-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel cyclic peptide, oriamide (1) containing the new 4-propenoyl-2-tyrosylthiazole amino acid (PTT), was isolated from the marine sponge Theonella sp. collected in Sodwana Bay. The structure of oriamide, including the absolute configuration of all amino acids, was elucidated by spectroscopic analysis and degradation experiments. (C) 1997 Elsevier Science Ltd.

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页码：16147 / 16152

页数：6

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