Use of Active Surveillance Cultures to Detect Asymptomatic Colonization With Carbapenem-Resistant Klebsiella pneumoniae in Intensive Care Unit Patients

被引:115
作者
Calfee, David [1 ]
Jenkins, Stephen G. [2 ]
机构
[1] Mt Sinai Sch Med, Dept Med, New York, NY 10029 USA
[2] Weill Cornell Med Coll, Dept Pathol, New York, NY USA
关键词
D O I
10.1086/590661
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Carbapenem-resistant Klebsiella pneumoniae is emerging as a significant healthcare-associated pathogen. Clinical cultures detect only a fraction of the colonized population, and patients with asymptomatic colonization are at risk of invasive infection. Additional study of the impact of detection of asymptomatic colonization on subsequent infection and transmission is needed.
引用
收藏
页码:966 / 968
页数:3
相关论文
共 11 条
[1]   Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 β-lactamases in New York City [J].
Bradford, PA ;
Bratu, S ;
Urban, C ;
Visalli, M ;
Mariano, N ;
Landman, D ;
Rahal, JJ ;
Brooks, S ;
Cebular, S ;
Quale, J .
CLINICAL INFECTIOUS DISEASES, 2004, 39 (01) :55-60
[2]   Detection of KPC carbapenem-hydrolyzing enzymes in Enterobacter spp. from Brooklyn, New York [J].
Bratu, S ;
Landman, D ;
Alam, M ;
Tolentino, E ;
Quale, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (02) :776-778
[3]   Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City -: A new threat to our antibiotic armamentarium [J].
Bratu, S ;
Landman, D ;
Haag, R ;
Recco, R ;
Eramo, A ;
Alam, M ;
Quale, J .
ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (12) :1430-1435
[4]   Emergence of KPC-possessing Klebsiella pneumoniae in Brooklyn, New York:: Epidemiology and recommendations for detection [J].
Bratu, S ;
Mooty, M ;
Nichani, S ;
Landman, D ;
Gullans, C ;
Pettinato, B ;
Karumudi, U ;
Tolaney, P ;
Quale, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (07) :3018-3020
[5]   Detection and spread of Escherichia coli possessing the plasmid-borne carbapenemase KPC-2 in Brooklyn, New York [J].
Bratu, Simona ;
Brooks, Steven ;
Burney, Sibte ;
Kochar, Sandeep ;
Gupta, Jyoti ;
Landman, David ;
Quale, John .
CLINICAL INFECTIOUS DISEASES, 2007, 44 (07) :972-975
[6]  
*CLSI, 2006, 16 INF S CLSI DOC WA
[7]   Risk factors of carbapenem-resistant Klebsiella pneumoniae infections:: a matched case-control study [J].
Falagas, Matthew E. ;
Rafailidis, Petros I. ;
Kofteridis, Diamantis ;
Virtzili, Simona ;
Chelvatzoglou, Fotini C. ;
Papaioannou, Vassiliki ;
Maraki, Sofia ;
Samonis, George ;
Michalopoulos, Argyris .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2007, 60 (05) :1124-1130
[8]  
KUHAR D, 2007, 17 ANN SCI M SOC HEA, P130
[9]   Evaluation of techniques for detection of carbapenem-resistant Klebsiella pneumoniae in stool surveillance cultures [J].
Landman, D ;
Salvani, JK ;
Bratu, S ;
Quale, J .
JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (11) :5639-5641
[10]  
PATEL G, 2007, 45 ANN M INF DIS SOC, P59