Chromatin remodeling and transcription

被引：176

作者：

Tsukiyama, T ^{[1
]}

Wu, C ^{[1
]}

机构：

[1] NCI,MOL CELL BIOL LAB,NIH,BETHESDA,MD 20892

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1997年 / 7卷 / 02期

关键词：

D O I：

10.1016/S0959-437X(97)80127-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent advances highlight two important chromatin remodeling systems involved in the transcriptional process. One system includes several members of the evolutionarily conserved SWI2/SNF2 family found in distinct multiprotein complexes with ATP-dependent nucleosome destabilizing activity; the other is the enzymatic system that governs histone acetylation and deacetylation. Identification of the catalytic subunits of these opposing histone-modifying activities reveal conserved proteins defined genetically as transcriptional regulators.

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页码：182 / 191

页数：10

相关论文

共 140 条

[11] Activator-dependent regulation of transcriptional pausing on nucleosomal templates [J].

Brown, SA ;

Imbalzano, AN ;

Kingston, RE .

GENES & DEVELOPMENT, 1996, 10 (12) :1479-1490

[12] Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation [J].

Brownell, JE ;

Zhou, JX ;

Ranalli, T ;

Kobayashi, R ;

Edmondson, DG ;

Roth, SY ;

Allis, CD .

CELL, 1996, 84 (06) :843-851

[13] Special HATs for special occasions: Linking histone acetylation to chromatin assembly and gene activation [J].

Brownell, JE ;

Allis, CD .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1996, 6 (02) :176-184

[14] AN ACTIVITY GEL ASSAY DETECTS A SINGLE, CATALYTICALLY ACTIVE HISTONE ACETYLTRANSFERASE SUBUNIT IN TETRAHYMENA MACRONUCLEI [J].

BROWNELL, JE ;

ALLIS, CD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (14) :6364-6368

[15] Essential role of Swp73p in the function of yeast Swi/Snf complex [J].

Cairns, BR ;

Levinson, RS ;

Yamamoto, KR ;

Kornberg, RD .

GENES & DEVELOPMENT, 1996, 10 (17) :2131-2144

[16] RSC, an essential, abundant chromatin-remodeling complex [J].

Cairns, BR ;

Lorch, Y ;

Li, Y ;

Zhang, MC ;

Lacomis, L ;

ErdjumentBromage, H ;

Tempst, P ;

Du, J ;

Laurent, B ;

Kornberg, RD .

CELL, 1996, 87 (07) :1249-1260

[17] A MULTISUBUNIT COMPLEX CONTAINING THE SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, AND SNF6 GENE-PRODUCTS ISOLATED FROM YEAST [J].

CAIRNS, BR ;

KIM, YJ ;

SAYRE, MH ;

LAURENT, BC ;

KORNBERG, RD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (05) :1950-1954

[18]

Candau R, 1996, MOL CELL BIOL, V16, P593

[19] THE SNF/SWI FAMILY OF GLOBAL TRANSCRIPTIONAL ACTIVATORS [J].

CARLSON, M ;

LAURENT, BC .

CURRENT OPINION IN CELL BIOLOGY, 1994, 6 (03) :396-402

[20] HDA1 and HDA3 are components of a yeast histone deacetylase (HDA) complex [J].

Carmen, AA ;

Rundlett, SE ;

Grunstein, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (26) :15837-15844

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