Croblongifolin, a new anticancer clerodane from Croton oblongifolius

被引:34
作者
Roengsumran, S [1 ]
Musikul, K
Petsom, A
Vilaivan, T
Sangvanich, P
Pornpakakul, S
Puthong, S
Chaichantipyuth, C
Jaiboon, N
Chaichit, N
机构
[1] Chulalongkorn Univ, Fac Sci, Dept Chem, Bangkok 10330, Thailand
[2] Thammasat Univ Rangsit, Fac Sci & Technol, Dept Phys, Pathum Thani, Thailand
[3] Chulalongkorn Univ, Inst Biotechnol & Genet Engn, Bangkok, Thailand
[4] Chulalongkorn Univ, Fac Pharmaceut Sci, Dept Pharmacognosy, Bangkok, Thailand
关键词
D O I
10.1055/s-2002-23138
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A new furoclerodane, croblongifolin, together with one known clerodane, crovatin and one known labdane, nidorellol, were isolated from the stem bark of Croton oblongifolius. Structures were established based on spectroscopic and X-ray analysis. Croblongifolin showed a significant cytotoxicity against various human tumor cell lines including HEP-G2, SW620, CHAGO, KATO3 and BT474.
引用
收藏
页码:274 / 277
页数:4
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