Influence of effector molecules on the CD8+ T cell response to infection

被引：79

作者：

Harty, JT

Badovinac, VP

机构：

[1] Univ Iowa, Dept Microbiol, Iowa City, IA 52242 USA

[2] Univ Iowa, Interdisciplinary Grad Program Immunol, Iowa City, IA 52242 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2002年 / 14卷 / 03期

关键词：

D O I：

10.1016/S0952-7915(02)00333-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Expansion and contraction of antigen-specific CD8(+) T cells after infection or vaccination results in stable memory, Recent evidence demonstrates that anti-microbial effector molecules such as perforin and IFN-gamma regulate specific aspects of CD8(+) T cell homeostasis by mechanisms that may be dependent or independent of pathogen clearance.

引用

页码：360 / 365

页数：6

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