Iron-Mediated Direct Arylation of Unactivated Arenes

被引：126

作者：

Wen, Jun ^{[1
]}

Zhang, Ji ^{[1
]}

Chen, Shan-Yong ^{[1
]}

Li, Jing ^{[1
]}

Yu, Xiao-Qi ^{[1
,2
]}

机构：

[1] Sichuan Univ, Dept Chem, Key Lab Green Chem & Technol, Minist Educ, Chengdu 610064, Peoples R China

[2] Sichuan Univ, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 46期

基金：

美国国家科学基金会;

关键词：

biaryls; boronic acids; C-H activation; cross-coupling; iron;

D O I：

10.1002/anie.200802526

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Inexpensive and straightforward: An iron-mediated cross-coupling reaction generates biaryl compounds through C-H bond activation, using easily handled reagents with low toxicity. Under the optimized reaction conditions a series of substituted phenylboronic acids were coupled with several simple unactivated arenes. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：8897 / 8900

页数：4

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