Nanomaterials based electrochemical sensors for biomedical applications

被引:734
作者
Chen, Aicheng [1 ]
Chatterjee, Sanghamitra [1 ]
机构
[1] Lakehead Univ, Dept Chem, Thunder Bay, ON P7B 5E1, Canada
基金
加拿大自然科学与工程研究理事会; 加拿大创新基金会;
关键词
GLASSY-CARBON ELECTRODE; PYROLYTIC-GRAPHITE ELECTRODE; TEMPERATURE IONIC LIQUIDS; HYDROGEN-PEROXIDE; DNA HYBRIDIZATION; GOLD NANOPARTICLES; ASCORBIC-ACID; SENSITIVE DETERMINATION; HORSERADISH-PEROXIDASE; PLATINUM NANOPARTICLES;
D O I
10.1039/c3cs35518g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A growing variety of sensors have increasingly significant impacts on everyday life. Key issues to take into consideration toward the integration of biosensing platforms include the demand for minimal costs and the potential for real time monitoring, particularly for point-of-care applications where simplicity must also be considered. In light of these developmental factors, electrochemical approaches are the most promising candidate technologies due to their simplicity, high sensitivity and specificity. The primary focus of this review is to highlight the utility of nanomaterials, which are currently being studied for in vivo and in vitro medical applications as robust and tunable diagnostic and therapeutic platforms. Highly sensitive and precise nanomaterials based biosensors have opened up the possibility of creating novel technologies for the early-stage detection and diagnosis of disease related biomarkers. The attractive properties of nanomaterials have paved the way for the fabrication of a wide range of electrochemical sensors that exhibit improved analytical capacities. This review aims to provide insights into nanomaterials based electrochemical sensors and to illustrate their benefits in various key biomedical applications. This emerging discipline, at the interface of chemistry and the life sciences, offers a broad palette of opportunities for researchers with interests that encompass nanomaterials synthesis, supramolecular chemistry, controllable drug delivery and targeted theranostics in biology and medicine.
引用
收藏
页码:5425 / 5438
页数:14
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