A Ratiometric Fluorescent Probe for Hypochlorite Based on a Deoximation Reaction

被引:257
作者
Lin, Weiying [1 ]
Long, Lingliang [1 ]
Chen, Bingbing [1 ]
Tan, Wen [1 ]
机构
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
基金
美国国家科学基金会;
关键词
charge transfer; fluorescence spectroscopy; fluorescent probes; hypochlorite; ratiometric; CARBONYL-COMPOUNDS; ACID; OXIMES; MYELOPEROXIDASE; SEMICARBAZONES; REGENERATION; HYDRAZONES; DISEASE; STRESS; CANCER;
D O I
10.1002/chem.200802054
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this work, we have successfully provided a novel strategy for the rational design and synthesis of a ratiometric fluorescent probe for hypochlorite, The strategy is based on the deoximation reaction, which has not yet been used in the fluorescent hypochlorite probe design. Interestingly, the probe showed a ratiometric fluorescent response to hypochlorite with the emission intensities ratio increasing from 0.28 to 2.74. Furthermore, the probe displayed high selectivity for hypochlorite over other species due to the distinct deoximation conditions. The probe developed herein represents the first ratiometric fluorescent probe for hypochlorite.
引用
收藏
页码:2305 / 2309
页数:5
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