Host-Intestinal Microbiota Mutualism: "Learning on the Fly"

被引：159

作者：

Erkosar, Berra ^{[1
]}

Storelli, Gilles ^{[1
]}

Defaye, Arnaud ^{[2
]}

Leulier, Francois ^{[1
]}

机构：

[1] Univ Lyon 1, IGFL, Ecole Normale Super Lyon, CNRS UMR 5242, F-69364 Lyon 07, France

[2] Aix Marseille Univ, INSERM UMR 1090, F-13288 Marseille 09, France

来源：

CELL HOST & MICROBE | 2013年 / 13卷 / 01期

关键词：

INNATE IMMUNE HOMEOSTASIS; DROSOPHILA-MELANOGASTER; LIFE-SPAN; TRADE-OFF; BACTERIA; GROWTH; IMPACT; MODEL; FLORA;

D O I：

10.1016/j.chom.2012.12.004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Given the complexity of the mammalian microbiota, there is a need for simple models to decipher the effector and regulatory mechanisms underlying host/microbiota mutualism. Approaches using Drosophila and its simple microbiota carry the potential to unravel the evolutionarily conserved mechanisms engaged in this association. Here, we review recent work carried out in this model, providing insights and exciting perspectives.

引用

页码：8 / 14

页数：7

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