Spectroscopic characterization of reaction intermediates in a model for copper nitrite reductase

被引：39

作者：

Kujime, M ^{[1
]}

Fujii, H

机构：

[1] Natl Inst Nat Sci, Inst Mol Sci, Okazaki, Aichi 4448787, Japan

[2] Natl Inst Nat Sci, Okazaki Inst Integrat Biosci, Okazaki, Aichi 4448787, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 07期

关键词：

bioinorganic chemistry; copper; enzyme models; reaction mechanisms; reactive intermediates;

D O I：

10.1002/anie.200503555

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) A nitrous acid complex was identified by spectroscopic and kinetic analyses under stopped-flow conditions as an intermediate in the reaction of copper(I) nitrite complex 1 with trifluoroacetic acid (see scheme). A reaction mechanism was proposed in which two protons are transferred in a stepwise manner to the nitrite anion. Intramolecular electron transfer from copper to the nitrite ligand occurs in the second protonation step. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1089 / 1092

页数：4

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