Inhibition of lipid peroxidation by sesquiterpenoid in Heterotheca inuloides

被引：18

作者：

Haraguchi, H

Saito, T

Ishikawa, H

Sanchez, Y

Ogura, T

Kubo, I

机构：

[1] UNIV NACL AUTONOMA MEXICO,DEPT QUIM,GUADALAJARA,JALISCO,MEXICO

[2] UNIV CALIF BERKELEY,DEPT ENVIRONM SCI POLICY & MANAGEMENT,BERKELEY,CA 94720

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1996年 / 48卷 / 04期

关键词：

D O I：

10.1111/j.2042-7158.1996.tb05949.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A sesquiterpenoid, 7-hydroxy-3,4-dihydrocadalin, isolated from a Mexican medicinal plant Heterotheca inuloides was evaluated as an antioxidant. This sesquiterpenoid inhibited mitochondrial and microsomal lipid peroxidation induced by Fe(III)-ADP/NADH or Fe(III)-ADP/NADPH. Furthermore, 7-hydroxy-3,4-dihydrocadalin protected red cells against oxidative haemolysis. This sesquiterpene was thus shown to be effective in protecting biological systems against oxidative stresses.

引用

页码：441 / 443

页数：3

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