Synthesis of Amidines Using N-Allyl Ynamides. A Palladium-Catalyzed Allyl Transfer through an Ynamido-π-Allyl Complex

被引：76

作者：

Zhang, Yu

DeKorver, Kyle A.

Lohse, Andrew G.

Zhang, Yan-Shi

Huang, Jian

Hsung, Richard P. ^{[1
]}

机构：

[1] Univ Wisconsin, Div Pharmaceut Sci, Madison, WI 53705 USA

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 04期

关键词：

ONE-POT SYNTHESIS; EFFICIENT SYNTHESIS; MULTICOMPONENT REACTION; TERMINAL ALKYNES; SULFONYL AZIDE; FACILE ACCESS; 1,3-DIPOLAR CYCLOADDITION; REDUCTIVE ELIMINATION; BICYCLIC AMIDINES; SECONDARY-AMINES;

D O I：

10.1021/ol802844z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A de novo transformation of N-allyl-N-sulfonyl ynamides to amidines is described featuring a palladium-catalyzed N-to-C allyl transfer via ynamido-palladium-pi-allyl complexes.

引用

收藏

页码：899 / 902

页数：4

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