Preparation of the neolignan natural product grossamide by a continuous-flow process

被引：146

作者：

Baxendale, IR ^{[1
]}

Griffiths-Jones, CM ^{[1
]}

Ley, SV ^{[1
]}

Tranmer, GK ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Innovat Technol Ctr, Cambridge CB2 1EW, England

来源：

SYNLETT | 2006年 / 03期

关键词：

poly mer-supported reagents; enzymes; flow synthesis; natural products;

D O I：

10.1055/S-2006-926244

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This article describes the first enantioselective total synthesis of 2-aryl-2,3-dihydro-3-beiizofurancarboxyamide neolignan, grossamide (1) using a fully automated and scalable flow reactor.

引用

页码：427 / 430

页数：4

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