Efficient Sonogashira, reactions of aryl bromides with alkynylsilanes catalyzed by a palladium/imidazolium salt system

被引:114
作者
Yang, CL [1 ]
Nolan, SP [1 ]
机构
[1] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA
关键词
D O I
10.1021/om011021k
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A palladium/imidazolium chloride system has been used to mediate the cross-coupling reaction of aryl halides with alkynylsilanes. The combination of 3 mol % Pd(OAc)(2) and 6 mol % IMes.HCl in the presence of Cs2CO3 as base proves to be a highly efficient system in assisting coupling of aryl bromides with alkynylsilanes.
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页码:1020 / 1022
页数:3
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