The application of vinylogous iminium salts and related synthons to the regiocontrolled preparation of 2,3- and 2,5-disubstituted pyrroles

被引：24

作者：

Gupton, JT

Petrich, SA

Smith, LL

Bruce, MA

Vu, P

Du, KX

Dueno, EE

Jones, CR

Sikorski, JA

机构：

[1] UNIV CENT FLORIDA,DEPT CHEM,ORLANDO,FL 32816

[2] MONSANTO CO,MONSANTO CORP RES,ST LOUIS,MO 63198

来源：

TETRAHEDRON | 1996年 / 52卷 / 20期

关键词：

D O I：

10.1016/0040-4020(96)00338-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 1-substituted vinamidinium salts with sarcosine ethyl ester produced 2,3-disubstituted pyrroles; a similar reaction with glycine ethyl ester gave 2,5-disubstituted pyrroles. Reactions of related three-carbon synthons with sarcosine and glycine were studied under basic, neutral and acidic conditions which demonstrated the utility of these derivatives for the regiocontrolled preparation of disubstituted pyrroles. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：6879 / 6892

页数：14

共 8 条

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